
Coffee Granate Forte, provided by Douglas
Laboratories®, is a synergistic blend of two unique extracts; a pomegranate
whole fruit extract standardized to punicosides and a whole coffee fruit extract
standardized to phenolic compounds. Together, these extracts provide strong
antioxidant and cardiovascular support. As science continues to uncover connections
between aging and free radical damage, antioxidants remain a vital safeguard in
helping to maintain proper redox status. Diets high in antioxidants, as well as
supplementation with antioxidants have been shown to have a protective effect in
reducing cellular damage caused by free radicals. Recent science has been
focusing on the antioxidant and cardioprotective aspects of pomegranate. These
brightly colored fruits contains numerous compounds known for their antioxidant
capabilities, including anthocyanidins, catechins, proanthocyanidins,
ellagitannins, gallotannins and ellagic, and gallic acids. While many
pomegranate extracts are standardized simply to ellagic acid, increasing
research indicates that some of the most beneficial constituents of the
pomegranate may in fact be the ellagitannins (also known as hydrolyzable
tannins). These ellagitannins can be found in relatively abundant quantities in
pomegranate juice. One family of ellagitannins, known as punicalagins, has been
shown to be especially important for supporting healthy cell growth and immune
function.* The pomegranate extract used in Coffee Granate Forte is standardized
to provide 40% punicosides, including punicalagins and punicalin. Though the
coffee bean is well known as the source of a common drink, the bright red fruit
surrounding the bean is becoming increasingly popular for the antioxidant
compounds it contains. Whole coffee fruit contains significantly higher levels
of antioxidants than brewed coffee; however modern coffee harvesting and
roasting practices discard much of the antioxidants found in the fruit and bean.
As a traditional food of native peoples, coffee fruit has a long history of
being used as a tea, wine, medicine and energy-providing food. The coffee fruit
extract used in Coffee Granate Forte is made from the fruit that surrounds the
bean and is particularly high in chlorogenic, caffeic, and ferulic acids and
possess a high ORAC (oxygen radical absorbance capcity) value. Coffee Granate may be a useful dietary adjunct for
individuals wishing to supplement their diets with a unique blend of
antioxidants. As a dietary supplement, take 1 capsule daily or
as directed by your healthcare professional. Keep out of reach of children. Adams LS, Seeram NP, Aggarwal BB, Takada Y, Sand D, Heber D.
Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress
inflammatory cell signaling in colon cancer cells. J Agric Food Chem. 2006
Feb 8;54(3):980-5. Hemmerle H, Burger HJ, Below P, et al. Chlorogenic acid and
synthetic chlorogenic acid derivatives: novel inhibitors of hepatic
glucose-6-phosphate translocase. J Med Chem. 1997 Jan 17;40(2):137-45. Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies
gastrointestinal hormone secretion and glucose tolerance in humans: glycemic
effects of chlorogenic acid and caffeine. Am J Clin Nutr. 2003
Oct;78(4):728-33 Lin CC, Hsu YF, Lin TC, Hsu HY. Antioxidant and
hepatoprotective effects of punicalagin and punicalin on
acetaminophen-induced liver damage in rats. Phytother Res. 2001
May;15(3):206-12. *These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure, or
prevent any disease.
Description
Functions
Indications
Suggested Use
Storage
References:
1 vegetarian capsule
contains:
Standardized pomegranate extract
150 mg
(whole fruit, standardized to 40%
punicodies, including
punicalagins and punicalin)
Standardized Coffee Fruit extract
150 mg
(50% phenolic acids, <0.5% caffeine)
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