<A HREF="http://www.thegreenpharmacy.com" TITLE="The Green Pharmacy"><IMG SRC="https://store.nexternal.com/greenpharm/Logo-9thvector_Nexternal.jpg" ALT="The Green Pharmacy" NAME="The Green Pharmacy" BORDER=0></A><BR> <H1>Coffee Granate Forte 60 caps -- The Green Pharmacy Shopping Cart</H1> <B>$32.00</B> -- <I>A Unique Combination of Standardized Pomegranate Fruit and Coffee Fruit Extracts</I> <P> <IMG SRC="https://store.nexternal.com/greenpharm/images/DL_Coffee_Grante_Forte.jpg" ALIGN=right ALT="Coffee Granate Forte 60 caps" NAME="Coffee Granate Forte 60 caps" BORDER=0 HSPACE=10> <style> <!-- h5 { font-family: Arial; font-size: 12pt; color: #008000; font-weight: bold; border-bottom: 1px dotted #008000; margin-top: 12; margin-bottom: 0; padding: 1px } numbered list small { list-style-type: decimal; font-family: Arial; font-size: 8pt; text-align: left; line-height: 11pt; margin-left: 5; margin-top: 6; margin-bottom: 6 } body { font-family: Arial; font-size: 11pt } .body1 { font-family: Arial; font-size: 11pt; line-height: 14pt; margin-top: 4; margin-bottom: 8 } .body2 { font-family: Arial; font-size: 11pt; line-height: 14pt; margin-top: 8; margin-bottom: 4 } .table1 { font-family: Arial; font-size: 12pt; color: #008000; font-weight: bold; padding-top: 1px; padding-bottom: 1px } --> </style> <font FACE="Arial-Bold"><b> <h5 ALIGN="LEFT">Description</h5> </b></font><font FACE="Arial" SIZE="1"> <p ALIGN="LEFT" class="body1">Coffee Granate Forte, provided by Douglas Laboratories&#174;, is a synergistic blend of two unique extracts; a pomegranate whole fruit extract standardized to punicosides and a whole coffee fruit extract standardized to phenolic compounds. Together, these extracts provide strong antioxidant and cardiovascular support.</p> </font><b> <h5 ALIGN="LEFT">Functions</h5> </b><font FACE="Univers" SIZE="1"> <p ALIGN="LEFT" class="body1">As science continues to uncover connections between aging and free radical damage, antioxidants remain a vital safeguard in helping to maintain proper redox status. Diets high in antioxidants, as well as supplementation with antioxidants have been shown to have a protective effect in reducing cellular damage caused by free radicals. Recent science has been focusing on the antioxidant and cardioprotective aspects of pomegranate. These brightly colored fruits contains numerous compounds known for their antioxidant capabilities, including anthocyanidins, catechins, proanthocyanidins, ellagitannins, gallotannins and ellagic, and gallic acids. While many pomegranate extracts are standardized simply to ellagic acid, increasing research indicates that some of the most beneficial constituents of the pomegranate may in fact be the ellagitannins (also known as hydrolyzable tannins). These ellagitannins can be found in relatively abundant quantities in pomegranate juice. One family of ellagitannins, known as punicalagins, has been shown to be especially important for supporting healthy cell growth and immune function.* The pomegranate extract used in Coffee Granate Forte is standardized to provide 40% punicosides, including punicalagins and punicalin. Though the coffee bean is well known as the source of a common drink, the bright red fruit surrounding the bean is becoming increasingly popular for the antioxidant compounds it contains. Whole coffee fruit contains significantly higher levels of antioxidants than brewed coffee; however modern coffee harvesting and roasting practices discard much of the antioxidants found in the fruit and bean. As a traditional food of native peoples, coffee fruit has a long history of being used as a tea, wine, medicine and energy-providing food. The coffee fruit extract used in Coffee Granate Forte is made from the fruit that surrounds the bean and is particularly high in chlorogenic, caffeic, and ferulic acids and possess a high ORAC (oxygen radical absorbance capcity) value.</p> </font><font FACE="Univers-Bold"><b> <h5 ALIGN="LEFT">Indications</h5> </b> <p ALIGN="LEFT" class="body1">Coffee Granate may be a useful dietary adjunct for individuals wishing to supplement their diets with a unique blend of antioxidants.</p> <b> <h5 ALIGN="LEFT">Suggested Use</h5> </b> <p ALIGN="LEFT" class="body1">As a dietary supplement, take 1 capsule daily or as directed by your healthcare professional.</p> <b> </b></font><font FACE="Univers" SIZE="1"> <font FACE="Univers-Bold"><b> <h5 ALIGN="LEFT">Storage</h5> </b></font> <p ALIGN="LEFT" class="body1">Keep out of reach of children.</p> </font><font FACE="Univers-Bold"><b> <h5 ALIGN="LEFT">References:</h5> </b></font><font SIZE="1"> <ol> <li> <p ALIGN="LEFT">Adams LS, Seeram NP, Aggarwal BB, Takada Y, Sand D, Heber D. Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells. J Agric Food Chem. 2006 Feb 8;54(3):980-5. </li> <li> <p ALIGN="LEFT">Hemmerle H, Burger HJ, Below P, et al. Chlorogenic acid and synthetic chlorogenic acid derivatives: novel inhibitors of hepatic glucose-6-phosphate translocase. J Med Chem. 1997 Jan 17;40(2):137-45. </li> <li> <p ALIGN="LEFT">Johnston KL, Clifford MN, Morgan LM. Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine. Am J Clin Nutr. 2003 Oct;78(4):728-33 </li> <li> <p ALIGN="LEFT">Lin CC, Hsu YF, Lin TC, Hsu HY. Antioxidant and hepatoprotective effects of punicalagin and punicalin on acetaminophen-induced liver damage in rats. Phytother Res. 2001 May;15(3):206-12.</li> </ol> <font face="Arial" size="2" color="#2A4591"> <b>1 vegetarian capsule contains:</b><table width="351" cellpadding="0" cellpadding="0"> <tr> <td width="270" background="/images/dots2.gif" nowrap> <font size="2" color="#2A4591">Standardized pomegranate extract</font></td><td width="75" background="/images/dots2.gif" align="right" nowrap> <font size="2" color="#2A4591">150 mg</font></td></tr> <tr> <td width="345" background="/images/dots2.gif" nowrap colspan="2"> <font size="2" color="#2A4591">&#160; (whole fruit, standardized to 40% punicodies, including</font></td></tr> <tr> <td width="270" background="/images/dots2.gif" nowrap> <font size="2" color="#2A4591">&#160; punicalagins and punicalin)</font></td><td width="75" background="/images/dots2.gif" align="right" nowrap> &#160;</td></tr> <tr> <td width="270" background="/images/dots2.gif" nowrap> <font size="2" color="#2A4591">Standardized Coffee Fruit extract</font></td><td width="75" background="/images/dots2.gif" align="right" nowrap> <font size="2" color="#2A4591">150 mg</font></td></tr> <tr> <td width="270" background="/images/dots2.gif" nowrap> <font size="2" color="#2A4591">&#160; (50% phenolic acids, <0.5% caffeine)</font></td><td width="75" background="/images/dots2.gif" align="right" nowrap> &#160;</td></tr> </table></font></font> <font face="Arial" color="#2A4591"> <p>*These statements have not been evaluated by the Food and Drug Administration. 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