
Alpha lipoic acid is an exceptionally versatile
nutrient. Being both water and fat soluble, it is able to function in almost any
part of the body. It is a potent antioxidant which enhances the activity of
vitamins C and E. It is a multifunctional compound providing protection from
free radicals and supporting various metabolic processes. It has been associated
with supporting nerve health, cardiovascular function, and glucose metabolism.* Nerve Health: At this time, as many as
fifteen clinical trials have examined the role of alpha lipoic acid in
maintaining healthy nerve function. The results of these trials have typically
demonstrated that alpha lipoic acid administration provides neuroprotection. In
part, this may be due to alpha lipoic acid’s ability to modulate nitric oxide
metabolite activity and to promote healthy microcirculation.* Glucose Metabolism: Alpha lipoic acid
supports healthy glucose uptake and helps to maintain healthy glucose
utilization. It also plays a role in moderating the formation of advanced
glycation end products.* Cardiovascular Support: In addition to
supporting healthy glucose metabolism, the antioxidant properties of alpha
lipoic acid also promote healthy vascular and blood vessel function.* Pure Encapsulations alpha lipoic acid is
synthetically produced and has a minimum purity of 99%. Vitamin C (ascorbyl
palmitate) is derived from corn dextrose fermentation. Hypo-allergenic plant
fiber is derived from pine cellulose. Pure Encapsulations recommends 100–1200 mg per
day, in divided doses, with meals. If pregnant or lactating, consult your physician
before taking this product. Alpha lipoic acid may cause gastrointestinal
discomfort in some individuals and should always be taken with meals. In rare
cases, alpha lipoic acid may also cause skin rash in sensitive individuals. At this time, there are no known adverse reactions
when taken in conjunction with medications. Jacob S, et al. Enhancement of glucose disposal in patients
with type 2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995
Aug;45(8):872-874. Ziegler D, Schatz H, Conrad F, Gries FA, Ulrich H, Reichel
G. Effects of treatment with the antioxidant alpha-lipoic acid on cardiac
autonomic neuropathy in NIDDM patients. A 4-month randomized controlled
multicenter trial (DEKAN Study). Diabetes Care.1997 Mar; 20(3): 369-73. Midaoui AE et al. Lipoic acid prevents hypertension,
hyperglycemia, and the increase in heart mitochondrial superoxide
production. Am J Hypertens. 2003 Mar; 16(3): 173-9. Nagamatsu M et al. Lipoic acid improves nerve blood flow,
reduces oxidative stress, and improves distal nerve conduction in
experimental diabetic neuropathy. Diabetes Care.1995 Aug; 18(8): 1160-7.
Haak E et al. Effects of alpha-lipoic acid on
microcirculation in patients with peripheral diabetic neuropathy. Exp Clin
Endocrinol Diabetes.2000; 108(3): 168-74. Morcos M et al. Effect of alpha-lipoic acid on the
progression of endothelial cell damage and albuminuria in patients with
diabetes mellitus: an exploratory study. Diabetes Res Clin Pract.2001 Jun;
52(3): 175-83. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes,
Inc. 30 mg. 1–2 capsules per day, in divided doses, with meals.
What Is It?
Uses For Alpha Lipoic Acid
What Is The Source?
Recommendations
Are There Any Potential Side Effects Or Precautions?
Are There Any Potential Drug Interactions?
References:
each vegetable capsule contains:
alpha lipoic acid (thioctic acid)
600 mg.
vitamin C (as ascorbyl palmitate)
(hypo-allergenic plant fiber added to
complete capsule volume requirement)
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