
ChromeMate®, provided by Douglas Laboratories®, is
a trace element supplement that contains chromium bound to nicotinic acid. Each
tablet provides 200 mcg of chromium in its non-toxic trivalent form. Chromium is generally accepted as an essential
trace mineral that potentiates insulin action and thus influences carbohydrate,
protein, and fat metabolism. The biologically active form of chromium, sometimes
called glucose tolerance factor (GTF), occurs naturally in brewers yeast. GTF
has been proposed to be a complex of chromium, nicotinic acid (vitamin B3), and
possibly the amino acids glycine, cysteine, and glutamic acid. Many attempts
have been made to isolate or synthesize natural GTF, but none have been entirely
successful. The most promising approach to natural GTF is chromium
polynicotinate, the active form of chromium in ChromeMate. No other synthetic
chromium complex comes as close to natural GTF as chromium polynicotinate
(niacin-bound chromium) in terms of biological activity and chemical structure.
Chromium absorption is typically less than 2% efficient and variable depending
on its chemical form. Studies have demonstrated that chromium from ChromeMate
has a higher bioavailability than other chromium compounds, such as chromium
picolinate or chloride. Tissues retained anywhere from 2 to 8 times more
chromium from ChromeMate compared to chromium picolinate or chromium chloride.
The typical dietary chromium intake in the U.S. can vary considerably depending
on eating habits. Meats and unrefined whole grain cereal products, especially
bran, are good sources of chromium. However, most self-selected diets contain
less than 50 mcg per day, which is below the minimum of the Estimated Safe and
Adequate Daily Dietary Intake established by the National Research Council, Food
and Nutrition Board. Chromium requirements may be increased with high intake of
refined carbohydrates and simple sugars, strenuous physical exercise or work,
infection, or physical trauma. ChromeMate may be given orally as a daily
supplement for individuals who wish to supplement their intake of chromium or
who have a demonstrated need for supplemental chromium in its active form due to
dietary deficiency or impaired metabolism. One tablet daily as a dietary supplement. Certain
individuals may be advised by their health care provider to take more than one
tablet daily. Take with food. No adverse effects have been reported. Store in a cool, dry place, away from direct
light. Keep out of reach of children. Olin KL et al. Comparative retention/absorption of
51chromium (51Cr) from 51Cr chloride, 51Cr nicotinate and 51Cr picolinate in
a rat model. Trace Elem Electrolytes 1994;11:182-186. Lefavi R et al. Lipid-lowering effect of a dietary nicotinic
acid-chromium (III) complex in male athletes. FASEB J 1991;5:A1645
(abstract). Mertz W. Chromium in human nutrition: a review. J Nutr
1993;123:626- 633. Mertz W. Effects and metabolism of glucose tolerance factor.
In: Present Knowledge in Nutrition, The Nutrition Foundation, Washington,
D.C., 1976. Ch. 36, pp. 365-372. Morris BW et al. The trace element chromium--a role in
glucose homeostasis. Am J Clin Nutr 1992;55:989-991. Urberg M et al. Hypocholesterolemic effects of nicotinic
acid and chromium supplementation. J Fam Prac 1988;27:603-606. Wallach S. Clinical and biochemical aspects of chromium
deficiency. J Am Coll Nutr 1985;4:107-120. *These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure, or
prevent any disease.
Description
Functions
Indications
Suggested Use
Side Effects/Warnings
Storage
References:
Each tablet
contains:
Chromium (polynicotinate*)
200 mcg
* ChromeMate® brand of niacin-bound GTF
chromium, U.S. patent
#4,923,855, InterHealth Company.
Other products in the category Categories / Minerals:
3A Calcium 167mg 150 caps -- Natural calcium hydroxide and calcium oxide with HAI, 150 capsules
3A Calcium Ultra 167mg 180 caps
Advanced Essential Minerals 180 caps
Alive w/iron
Alive! Effervescent 15 pkts
Alive! Ultra-Shake - Apple & Cinnamon
Alive! Ultra-Shake Vanilla
Alive! w/ Iron 90 vcaps
Alive! w/o Iron 90 vcaps
Alive!® (no iron added) -- Quickly Absorbed
Amino-Iron™ 18 mg 100 tabs -- highly bioavailable and exceptionally well tolerated
Amino-Mag 200 mg 100 tabs -- Magnesium Amino Acid Chelate
Basic Minerals™ 180 caps -- A Comprehensive Mineral/Trace Element Formula
Basic Preventive® 1 (plus iron and copper) 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 2 (iron and copper free) 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 3 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 4 (iron and copper free) 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 5 (Iron Free) 270 vcaps -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 5 (w/ CU w/o Glands and FE) 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 5 (with extra D) 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® Junior 90 chews -- Multiple Vitamin-Mineral-Trace Element Supplement
Bone Restore, 150 caps
C.F.S. Support Formula™ 120 tabs -- Support for individuals affected by fatigue
Ca/Mg 2:1 90 vcaps
Cal/Mag 1001 -- Osteo-Support
Cal/Mag 2001 -- Osteo-Support
Cal-6 + Mg™ -- Osteo Support
Calcigard® 250 mg 90 tabs -- Bioavailable Calcium Citrate
Calcigard® 250 mg with Vitamin D 90 tabs -- Bioavailable Calcium Citrate
Calcigard® One-to-One 125 mg 90 tabs -- Calcium Citrate Plus Magnesium Amino Acid Chelate
Calcigard® One-to-One with Vitamin D 125 mg 90 tabs -- Calcium Citrate Plus Magnesium Amino Acid Chelate
Calcigard® Two-to-One with Vitamin D 90 tabs -- Calcium Citrate Plus Magnesium Amino Acid Chelate
Calcium Citrate -- Osteo Support
Calcium Citrate with Vitamin D, 300 capsules
Calcium Microcrystalline Hydroxyapatite -- Osteo Support
Chelated Magnesium 100 mg 100 tabs -- Cardiovascular Health, Osteo Support
Chewable Calcium 250 mg 120 tabs
Chewable Calcium 250 mg 60 tabs
Cholo-SYN™ 120 caps -- Cardiovascular Health
Chromium Picolinate 250 mcg. 100 caps -- Supports Healthy Blood Sugar Levels
Chromium-GTF 200 mcg 100 caps -- Biologically Active Chromium Supplement Chromium Polynicotinate
CNCR Support Formula™ 120 tabs -- Nutritional support for immune conditions
Complete Mineral Complex 90 caps -- This iron-free mineral formula contains the finest chelated minerals from Albion Advanced Nutrition for optimal absorption and utilization.
Copper 2 mg 100 caps -- Amino Acid Chelate
DGST Support Formula™ 120 tabs -- Improved food utilization
Dual-Source Chromium -- Supports Healthy Glucose Metabolism
Dyna-Cal -- Osteo-Support
Energy/Sports Pack 30 pkts -- Replacement for nutrient depletion during exercise
EPD Formula 180 tabs -- Physician Formulated for Enzyme Potentiated Desensitization
Essential Basics™ 180 caps -- Multiple Vitamin/Mineral/Trace Element Supplement