
Cal Chew chewable tablets, provided by Douglas
Laboratories®, offer an easily consumed formulation of calcium and vitamin D
specifically designed to maintain healthy bone structure and function. The adult human body contains approximately 1,200
g of calcium, about 99% of which is present in the skeleton. Bone is constantly
turning over, a continuous process of formation and resorption. In children and
adolescents, the rate of formation of bone mineral predominates over the rate of
resorption. In later life, resorption predominates over formation. Therefore, in
normal aging, there is a gradual loss of bone. Osteoporosis, a condition of
reduced bone mineral density that can increase risk of fractures, affects a
large proportion of the elderly in developed countries. Caucasian and Asian
women typically have low peak bone densities, and therefore, are at the greatest
risk of developing osteoporosis. It is generally accepted that obtaining enough
dietary calcium throughout life can significantly decrease the risk of
developing osteoporosis. Among other factors, such as regular exercise, gender
and race, calcium supplementation during childhood and adolescence appears to be
a prerequisite for maintaining adequate bone density later in life. But even
elderly osteoporotic patients can benefit significantly from supplementation
with dietary calcium. Vitamin D is a key regulatory hormone for calcium
and bone metabolism. Intestinal calcium absorption ranges from 15 to 75% of
ingested calcium. Adequate vitamin D status is essential for ensuring normal
calcium absorption and maintenance of healthy calcium plasma levels. People
living in southern regions of the U.S. can derive significant amounts of vitamin
D from sunlight dependent synthesis in the skin during the summer, whereas
people in the northern latitudes have to rely more on foods and supplements for
adequate vitamin D status. Vitamin D also acts on tissue not related to calcium
metabolism. Studies have found receptors for vitamin D metabolites in a wide
variety of tissues ranging from the colon to the ovary. Cal Chew tablets may be a useful dietary
supplement for those who wish to have a more easily consumed source of calcium
and vitamin D to maintain healthy bones. Adults take 1 tablet 1 half hour before morning,
noon, and evening meals or as directed by physician. No adverse effects have been reported. Store in a cool, dry place, away from direct
light. Keep out of reach of children. Arikoski P, Kroger H, Riikonen P, et al. Disturbance in bone
turnover in children with a malignancy at completion of chemotherapy. Med
Pediatr Oncol 1999;33:455-61. Baker SS, Cochran WJ, Flores CA, et al. American Academy of
Pediatrics. Committee on Nutrition. Calcium requirements of infants,
children, and adolescents. Pediatrics 1999;104:1152-7. Barger-Lux MJ, Heaney RP. The role of calcium intake in
preventing bone fragility, hypertension, and certain cancers. J Nutr
1994;124:1406S-1411S. Bryant RJ, Cadogan J, Weaver CM. The new dietary reference
intakes for calcium: implications for osteoporosis. J Am Coll Nutr
1999;18:406S-412S. Heaney RP, Dowell MS, Barger-Lux MJ. Absorption of calcium
as the carbonate and citrate salts, with some observations on method.
Osteoporos Int 1999;9:19-23. Heaney RP. Calcium, dairy products and osteoporosis. J Am
Coll Nutr 2000;19:83S-99S. Kyriakidou-Himonas M, Aloia JF, Yeh JK. Vitamin D
supplementation in postmenopausal black women. J Clin Endocrinol Metab
1999;84:3988-90. Marci CD, Viechnicki MB, Greenspan SL. Bone mineral
densitometry substantially influences health-related behaviors of
postmenopausal women. Calcif Tissue Int 2000;66:113-8. Melin AL, Wilske J, Ringertz H, et al. Vitamin D status,
parathyroid function and femoral bone density in an elderly Swedish
population living at home. Aging (Milano) 1999;11:200-7. Morselli B, Neuenschwander B, Perrelet R, et al.
[Osteoporosis diet]. Ther Umsch 2000;57:152-60. Reid IR. The roles of calcium and vitamin D in the
prevention of osteoporosis. Endocrinol Metab Clin North Am 1998;27:389-98.
Storm D, Eslin R, Porter ES, et al. Calcium supplementation
prevents seasonal bone loss and changes in biochemical markers of bone
turnover in elderly New England women: a randomized placebocontrolled trial.
J Clin Endocrinol Metab 1998;83:3817-25. *These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure, or
prevent any disease.
Description
Functions
Indications
Suggested Use
Side Effects/Warnings
Storage
References:
Three chewable
tablets contain:
Calcium (Carbonate)
1,000 mg
Vitamin D
400 I.U.
With fructose and natural orange-vanilla
flavoring
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