
l-Arginine is a safe, versatile amino acid
supporting protein synthesis and serving as a precursor of nitric oxide.* Cardiovascular Health: In the body, the
metabolism of l-arginine leads to the formation of nitric oxide. Arginine-derived
nitric oxide is an important catalyst for healthy dilation of blood vessels,
circulation, and blood flow. In a prospective, double-blind trial, l-arginine
supplementation supported healthy endothelial function in blood vessels of male
volunteers. In other studies, l-arginine promoted healthy platelet function and
enhanced exercise tolerance. Additional trials indicate that l-arginine may
support healthy lipid metabolism and moderate lipid peroxidation, enhancing its
cardiovascular support properties.* Support For Immune Function And Healthy
Tissues: Arginine has demonstrated immuno-stimulatory activity and may
promote the utilization of nitric oxide by scavenger cells for defense
mechanisms. Enhancement of immune messenger compounds has also been observed in
several studies with l-arginine. In a study involving elderly individuals, l-arginine
facilitated healthy tissue recovery, accelerated tissue repair and supported
immune health.* Male Sexual Function: In men with low
urinary nitric oxide values, l-arginine may support healthy sexual performance.
Some but not all research involving l-arginine supplementation for sperm
motility have produced positive results.* Growth Hormone Support: Arginine plays
a role in the synthesis of hormones such as insulin and growth hormone, and has
demonstrated the potential to support glucose metabolism and growth hormone
production respectively.* Memory: Nitric oxide is also a mediator of
neurotransmission in the brain, supporting memory under the circumstances of
reduced intracellular arginine.* l-Arginine HCl is derived from the fermentation of
soy and other vegetable sources and is ultra-filtered and highly purified. Pure Encapsulations recommends 2-6 capsules
(1500-4500 mg l-arginine HCl) per day, in divided doses, between meals. If pregnant or lactating, consult your physician
before taking this product. Because of its effect on nitric oxide production, l-arginine
is theoretically best avoided by individuals with migraines, depression,
autoimmune disorders, and kidney or liver disease. Arginine is contraindicated
for individuals with the herpes virus. At this time, there are no known adverse reactions
when taken in conjunction with medications. Siani A et al. Blood pressure and metabolic changes during
dietary Larginine supplementation in humans. Am J Hyperten 2000 May;13(5 Pt
1):547- 51. Wolf A, Zalpour C, Theilmeier G, et al. Dietary L-arginine
supplementation normalizes platelet aggregation in hypercholesterolemic
humans. J Am Coll Cardiol1997;29:479-85. Sozykin Av et al. Effect of L-arginine on platelet
aggregation, endothelial function and exercise tolerance in patients with
stable angina pectoris. Ter Arkh.2000;72(8):24-7. Bednarz B, et al. Effects of oral L-arginine supplementation
on exerciseinduced QT dispersion and exercise tolerance in stable angina
pectoris. Int J Cardiol.2000 Sep 15;75(2-3):205-10. Adams MR et al. Oral L-arginine improves
endothelium-dependent dilatation and reduces monocyte adhesion to
endothelial cells in young men with coronary artery disease.
Atherosclerosis. 1997 Mar 21;129(2):261-9. Kirk SJ, Hurson M, Regan MC, et al. Arginine stimulates
wound healing and immune function in elderly human beings.
Surgery1993;114:155-60. Besset A, Bonardet A, Rondouin G, et al. Increase in sleep
related GH and Prl secretion after chronic arginine aspartate administration
in man. Acta Endocrinol1982;99:18-23. Chen J et al. Effect of oral administration of high-dose
nitric oxide donor L-arginine in men with organic erectile dysfunction:
results of a doubleblind, randomized, placebo-controlled study. BJU
Int.1999 Feb;83(3):269-73. Kuiper MA et al. Decreased cerebrospinal fluid nitrate
levels in Parkinson's disease, Alzheimer's disease and multiple system
atrophy patients. J Neurol Sci.1994 Jan;121(1) 46-9. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes,
Inc.
What Is It?
Uses For l-Arginine
What Is The Source?
Recommendations
Are There Any Potential Side Effects Or Precautions?
Are There Any Potential Drug Interactions?
References:
each vegetable capsule contains:
l-arginine HCl
750 mg.
2–6 capsules per day, in divided doses, between meals.
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