
Calcigard® One-to-One provides equal amounts of
calcium as calcium citrate, and magnesium as amino acid chelate, both with
excellent bioavailability. This formula, manufactured by Douglas Laboratories,
is available with and without added vitamin D. The adult human body contains approximately 1,200
g of calcium, of which about 99% is present in the skeleton, and 20-30 g of
magnesium with about 60% located in bone. The remaining 1% of total body calcium
and 40% of total body magnesium are found in the soft tissues and play important
roles in such vital functions as nerve conduction, muscle contraction, energy
metabolism, blood clotting, membrane permeability, and hormonal signaling. Blood
calcium levels are carefully maintained within very narrow limits by the
interplay of several hormones (1,25-dihydroxy-cholecalciferol, parathyroid
hormone, calcitonin, estrogen, and testosterone) which control calcium
absorption and excretion, as well as bone metabolism. The intracellular levels
of magnesium are also very tightly regulated, since their alterations can have
profound effects on cardiac and skeletal muscle physiology. Intestinal calcium
absorption ranges from 15 to 75% of ingested calcium. Adequate vitamin D status
is necessary for normal calcium absorption. Magnesium absorption is independent
of vitamin D status and ranges from 30 to 60% of ingested magnesium. Bone is
constantly turning over, through a continuous process of formation and
resorption. In children and adolescents, the rate of formation of bone mineral
predominates over the rate of resorption. In later life, resorption predominates
over formation. Therefore, in normal aging, there is a gradual loss of bone.
Osteoporosis afflicts a large proportion of the elderly in developed countries.
Caucasian and Asian women typically have low peak bone densities, and are
therefore at the greatest risk of developing osteoporosis. It is generally
accepted that obtaining enough dietary calcium throughout life can significantly
decrease the risk of developing osteoporosis. Among other factors, such as
regular exercise, gender and race, calcium supplementation during childhood and
adolescence appears to be a prerequisite for maintaining adequate bone density
later in life. But even elderly osteoporotic patients can benefit significantly
from supplementation with dietary calcium and magnesium. Calcigard One-to-One
provides highly beneficial sources of both calcium and magnesium. They are well
absorbed and well tolerated. Vitamin D is a key regulatory hormone for calcium
and bone metabolism. Adequate vitamin D intake is important for ensuring normal
calcium absorption and maintaining proper calcium plasma levels. People living
in southern regions of the U.S. can derive significant amounts of vitamin D from
sunlight dependent synthesis in the skin during the summer, whereas people in
the northern states have to rely more on foods and supplements for adequate
vitamin D status. This is why Calcigard formulas are available both with and
without vitamin D. Calcigard One-to-One may be useful dietary
supplement for those at risk for osteoporosis, or anyone who wishes to increase
their intake of calcium and magnesium for maintaining good bone health. Calcigard One-to-One: One to four tablets daily as
a dietary supplement, or as directed by a physician. Take with food. No adverse effects have been reported. Store in a cool, dry place, away from direct
light. Keep out of reach of children. Abbott L, Nadler J, Rude RK. Magnesium deficiency in
alcoholism: Possible contribution to osteoporosis and cardiovascular disease
in alcoholics. Alcoholism (NY) 1994;18:1076-1082. Andon MB, Lloyd T, Matkovic V. Supplementation trials with
calcium citrate malate: Evidence in favor of increasing the calcium RDA
during childhood and adolescence. J Nutr 1994;124 Suppl.1412S- 417S. Barger-Lux MJ, Heaney RP. The role of calcium intake in
preventing bone fragility, hypertension, and certain cancers. J Nutr
1994;124 Suppl.1406S-1411S. Belizan JM, Villar J, Bergel E, Pino Ad, Di Fulvio S,
Galliano SV, and Kattan C. Long term effect of calcium supplementation
during pregnancy on the blood pressure of offspring: follow up of a
randomised controlled trial. BMJ 1997;315(7013):281-5. Bronner F. Calcium and osteoporosis. Am J Clin Nutr
1994;60:831- 836. Durlach J, Durlach V, Bac P, Rayssiguier Y, Bara M, Guiet-Bara
A. Magnesium and ageing. II. Clinical data: Aetiological mechanisms and
pathophysiological consequences of magnesium deficit in the elderly. Magnes
Res 1993;6:379-394. Fleming KH, Heimbach JT. Consumption of calcium in the U.S.:
Food sources and intake levels. J Nutr 1994;124 Suppl.1426S-1430S. Horowitz M, Wishart JM, Goh D, Morris HA, Need AG, Nordin
BEC. Oral calcium suppresses biochemical markers of bone resorption in
normal men. Am J Clin Nutr 1994;60:965-968. Levine BS, Rodman JS, Wienerman S, Bockman RS, Lane JM,
Chapman DS. Effect of calcium citrate supplementation on urinary calcium
oxalate saturation in female stone formers: Implications for prevention of
osteoporosis. Am J Clin Nutr 1994;60:592-596. Reid IR, Ames RW, Evans MC, Gamble GD, Sharpe SJ. Long-term
effects of calcium supplementation on bone loss and fractures in
postmenopausal women: A randomized controlled trial. Am J Med
1995;98:331-335. Sojka JE, Weaver CM. Magnesium supplementation and
osteoporosis. Nutr Rev 1995;53:71-74. Strause L, Saltman P, Smith KT, Bracker M, Andon MB. Spinal
bone loss in postmenopausal women supplemented with calcium and trace
minerals. J Nutr 1994;124:1060-1064. Teegarden D, Weaver CM. Calcium supplementation increases
bone density in adolescent girls. Nutr Rev 1994;52:171-173. *These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure, or
prevent any disease.
Description
Functions
Indications
Suggested Use
Side Effects/Warnings
Storage
References:
Each tablet
contains:
Miller GD, Weaver CM. Required versus optimal intakes: A look at calcium. J
Nutr 1994;124 Suppl.1404S-1405S.
Calcium (citrate)
125 mg**
Magnesium (amino acid chelate)
125 mg**
Vitamin D3 (fish liver oil)***
25 IU
Other products in the category Categories / Minerals:
3A Calcium 167mg 150 caps -- Natural calcium hydroxide and calcium oxide with HAI, 150 capsules
3A Calcium Ultra 167mg 180 caps
Advanced Essential Minerals 180 caps
Alive w/iron
Alive! Effervescent 15 pkts
Alive! Ultra-Shake - Apple & Cinnamon
Alive! Ultra-Shake Vanilla
Alive! w/ Iron 90 vcaps
Alive! w/o Iron 90 vcaps
Alive!® (no iron added) -- Quickly Absorbed
Amino-Iron™ 18 mg 100 tabs -- highly bioavailable and exceptionally well tolerated
Amino-Mag 200 mg 100 tabs -- Magnesium Amino Acid Chelate
Basic Minerals™ 180 caps -- A Comprehensive Mineral/Trace Element Formula
Basic Preventive® 1 (plus iron and copper) 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 2 (iron and copper free) 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 3 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 4 (iron and copper free) 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 5 (Iron Free) 270 vcaps -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 5 (w/ CU w/o Glands and FE) 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® 5 (with extra D) 180 tabs -- Multiple Vitamin-Mineral-Trace Element Supplement
Basic Preventive® Junior 90 chews -- Multiple Vitamin-Mineral-Trace Element Supplement
Bone Restore, 150 caps
C.F.S. Support Formula™ 120 tabs -- Support for individuals affected by fatigue
Ca/Mg 2:1 90 vcaps
Cal/Mag 1001 -- Osteo-Support
Cal/Mag 2001 -- Osteo-Support
Cal-6 + Mg™ -- Osteo Support
Calcigard® 250 mg 90 tabs -- Bioavailable Calcium Citrate
Calcigard® 250 mg with Vitamin D 90 tabs -- Bioavailable Calcium Citrate
Calcigard® One-to-One 125 mg 90 tabs -- Calcium Citrate Plus Magnesium Amino Acid Chelate
Calcigard® Two-to-One with Vitamin D 90 tabs -- Calcium Citrate Plus Magnesium Amino Acid Chelate
Calcium Citrate -- Osteo Support
Calcium Citrate with Vitamin D, 300 capsules
Calcium Microcrystalline Hydroxyapatite -- Osteo Support
Chelated Magnesium 100 mg 100 tabs -- Cardiovascular Health, Osteo Support
Chewable Calcium 250 mg 120 tabs
Chewable Calcium 250 mg 60 tabs
Cholo-SYN™ 120 caps -- Cardiovascular Health
ChromeMate® 200 mcg 100 tabs -- Biologically Active Chromium Supplement Chromium Polynicotinate
Chromium Picolinate 250 mcg. 100 caps -- Supports Healthy Blood Sugar Levels
Chromium-GTF 200 mcg 100 caps -- Biologically Active Chromium Supplement Chromium Polynicotinate
CNCR Support Formula™ 120 tabs -- Nutritional support for immune conditions
Complete Mineral Complex 90 caps -- This iron-free mineral formula contains the finest chelated minerals from Albion Advanced Nutrition for optimal absorption and utilization.
Copper 2 mg 100 caps -- Amino Acid Chelate
DGST Support Formula™ 120 tabs -- Improved food utilization
Dual-Source Chromium -- Supports Healthy Glucose Metabolism
Dyna-Cal -- Osteo-Support
Energy/Sports Pack 30 pkts -- Replacement for nutrient depletion during exercise
EPD Formula 180 tabs -- Physician Formulated for Enzyme Potentiated Desensitization
Essential Basics™ 180 caps -- Multiple Vitamin/Mineral/Trace Element Supplement