
Glycine is the simplest amino acid; its side chain
consists of just a single hydrogen atom. Because of its simplicity, it has only
one form, not two (l- or d-) like other amino acids. It is an abundant amino
acid and is not considered essential. Supplementation with glycine, however, has
been shown to support healthy kidney and liver function as well as nervous
system health.* Cognitive Support: In animal studies and in
a small human study, glycine demonstrated the potential to support memory and
mental function. In another human trial, glycine, acting as an inhibitory amino
acid, had neuroprotective effects. * Detoxification Support: Animal studies
suggest that glycine plays a protective role for the kidneys and liver
particularly by supporting detoxification of certain chemicals. Glycine has also
been shown to moderate the release of cytokines during times of metabolic
stress.* Glycine is synthetically produced. Vitamin C (ascorbyl
palmitate) is derived from corn dextrose fermentation. Hypo-allergenic plant
fiber is derived from pine cellulose. Pure Encapsulations recommends 3-6 capsules
(1500-3000 mg.) daily, in divided doses, between meals. Glycine may be contraindicated for those
immediately recovering from stroke or with liver and kidney disease. If pregnant
or lactating, consult your physician before taking this product. Glycine may be contraindicated for those taking
clozapine, an antipsychotic medication. Deters M, Siegers CP, Strubelt O. Influence of glycine on
the damage induced in isolated perfused rat liver by five hepatotoxic
agents. Toxicology 1998 Jun 26;128(1):63-72. Shaikh ZA, Tang W. Protection against chronic cadmium
toxicity by glycine. Toxicology 1999 Feb 15;132(2-3):139-46. Matilla B, Mauriz JL, Culebras JM, Gonzalez-Gallego J,
Gonzalez P. Glycine: a cell-protecting anti-oxidant nutrient. Nutr Hosp 2002
Jan- Feb;17(1):2-9. File SE, Fluck E, Fernandes C. Beneficial effects of glycine
(bioglycin) on memory and attention in young and middle-aged adults. J Clin
Psychopharmacol 1999 Dec;19(6):506-12. Yin M, Ikejima K, Arteel GE, Seabra V, Bradford BU, Kono H,
Rusyn I, Thurman RG. Glycine accelerates recovery from alcohol-induced liver
injury. J Pharmacol Exp Ther 1998 Aug;286(2):1014-9. Baines AD, Shaikh N, Ho P. Mechanisms of perfused kidney
cytoprotection by alanine and glycine. Am J Physiol 1990 Jul;259(1 Pt
2):F80-7. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes,
Inc.
20 mg.
What Is It?
Uses For Glycine
What Is The Source?
Recommendations
Are There Any Potential Side Effects Or Precautions?
Are There Any Potential Drug Interactions?
References:
each vegetable capsule contains:
glycine (free-form)
500 mg.
vitamin C (as ascorbyl palmitate)
(hypo-allergenic plant fiber
added to complete capsule volume requirement)
3–6 capsules per day, in divided doses, between meals.
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