
Methylcobalamin is an activated, highly
bioavailable form of vitamin B12, which acts as the principal circulating form
of cobalamin in the body. It is available in liquid and capsule form.* Nervous System Health: In recent studies,
methylcobalamin has demonstrated an enhanced ability to support neurological
function. This form of vitamin B12 promotes protein synthesis for maintaining
healthy nerve cells and myelin. Methylcobalamin may also help to moderate levels
of glutamate in the brain, encouraging healthy brain cell activity, as well as
memory, mood, and cognitive function. In general, vitamin B12 works with folate
to promote DNA and red blood cell health. Additionally, vitamin B12 is an
important cofactor for energy metabolism and a vital component of the methionine
synthase pathway, which supports healthy homocysteine metabolism and
S-adenosylmethionine (SAMe) production.* Pure Encapsulations methylcobalamin is produced
from corn dextrose fermentation. It has a naturally occurring red color that
does not result from the use of artificial dyes or colors. Neither the capsule
or liquid product contains added/artificial sugars or added color. Pure Encapsulations recommends: • 1-3 capsules per day, in divided doses, with
meals. • 1-3 ml daily, in divided doses, with meals. At this time, there are no known side effects or
precautions. If pregnant or lactating, consult your physician before taking this
product. At this time, there are no known adverse reactions
when taken in conjunction with medications. Shimizu N, Hamazoe R, Kanayama H, Maeta M, Koga S.
Experimental study of antitumor effect of methyl-B12. Oncology
1987;44(3):169-73. Weinberg JB, Shugars DC, Sherman PA, Sauls DL, Fyfe JA.
Cobalamin inhibition of HIV-1 integrase and integration of HIV-1 DNA into
cellular DNA. Biochem Biophys Res Commun 1998 May 19;246(2) 393-7. Akaike A, Tamura Y, Sato Y, Yokota T. Protective effects of
a vitamin B12 analog, methylcobalamin, against glutamate cytotoxicity in
cultured cortical neurons. Eur J Pharmacol 1993 Sep 7;241(1):1-6. Waikakul W, Waikakul S. Methylcobalamin as an adjuvant
medication in conservative treatment of lumbar spinal stenosis. J Med Assoc
Thai 2000 Mayer G, Kroger M, Meier-Ewert K. Effects of vitamin B12 on
performance and circadian rhythm in normal subjects. Neuropsychopharmacology
1996 Nov;15(5):456-64. Yamashiki M, Nishimura A, Kosaka Y. Effects of
methylcobalamin (vitamin B12) on in vitro cytokine production of peripheral
blood mononuclear cells. J Clin Lab Immunol 1992;37(4):173-82. Healthnotes Clinical Essentials. Copyright 2005. Healthnotes,
Inc.
0.5 mg.
What Is It?
Uses For Methylcobalamin
What Is The Source?
Recommendations
Are There Any Potential Side Effects Or Precautions?
Are There Any Potential Drug Interactions?
References:
1 ml contains:
Aug;83(8):825-3.
methylcobalamin (B12)
1,000 mcg.
stevia
other ingredients: purified
water, natural glycerin
1–3 ml daily, in divided doses, with meals, or as directed by your health care practitioner.
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