
Cinnulin PF™ is a patented, concentrated cinnamon
(Cinnamomi cassia) extract. The 100% water-soluble product undergoes a
specialized extraction process that maintains the natural content of cinnamon’s
polyphenol polymers.* Healthy Glucose Metabolism: There has been
a growing amount of literature, including a study performed at the Beltsville
USDA Human Nutrition Research Center, suggesting that cinnamon’s water-soluble
polyphenol polymers support healthy glucose metabolism. A clinical trial
reported that supplementation with cinnamon promoted healthy glucose balance and
was well tolerated. Additional studies indicate that cinnamon extract promotes
an upregulation of glucose metabolism in skeletal muscle cells. Furthermore, an
animal study currently underway at the University of California at Santa Barbara
is further exploring, at a cellular level, the potential for cinnamon to support
glucose function.* Cardiovascular Function: A clinical trial
reported that cinnamon provided statistically significant support for healthy
lipid and triglyceride metabolism. Studies also indicate that the numerous
water-soluble polyphenol polymers found naturally in cinnamon may support
healthy blood flow and provide antioxidant protection.* Pure Encapsulations Cinnulin PF™ is derived from
cinnamon (Cinnamomi cassia) extract (20:1) (bark). Vitamin C (ascorbyl palmitate)
is derived from corn dextrose fermentation and palm oil. Hypo-allergenic plant
fiber is derived from pine cellulose. Cinnulin PF™ is a registered trademark of
Integrity Nutraceuticals International. US Patent # 6,200,569. Pure Encapsulations recommends 2 capsules per day,
in divided doses, with meals. Not to be taken by pregnant or lactating women.
Individuals with an allergy to cinnamon should avoid this product. At this time, there are no known adverse reactions
when taken in conjunction with medications. Qin B, Nagasaki M, Ren M, Bajotto G, Oshida Y, Sato Y.
Cinnamon Extract Prevents the Insulin Resistance Induced by a High-fructose
Diet. Horm Metab Res. 2004 Feb;36(2):119-25. Qin B, Nagasaki M, Ren M, Bajotto G, Oshida Y, Sato Y.
Cinnamon extract (traditional herb) potentiates in vivo insulin-regulated
glucose utilization via enhancing insulin signaling in rats. Diabetes Res
Clin Pract. 2003 Dec;62(3):139-48. Anderson RA, Broadhurst CL, Polansky MM, Schmidt WF, Khan A,
Flanagan VP, Schoene NW, Graves DJ. Isolation and characterization of
polyphenol type-A polymers from cinnamon with insulin-like biological
activity. J Agric Food Chem. 2004 Jan 14;52(1):65-70. Khan A, Safdar M, Ali Khan MM, Khattak KN, Anderson RA.
Cinnamon improves glucose and lipids of people with type 2 diabetes.
Diabetes Care. 2003 Dec;26(12):3215-8. Broadhurst CL, Polansky MM, Anderson RA. Insulin-like
biological activity of culinary and medicinal plant aqueous extracts in
vitro. J Agric Food Chem. 2000 Mar;48(3):849-52. Onderoglu S, Sozer S, Erbil KM, Ortac R, Lermioglu F. The
evaluation of long-term effects of cinnamon bark and olive leaf on toxicity
induced bystreptozotocin administration to rats. J Pharm Pharmacol. 1999
Nov;51(11):1305-12. Imparl-Radosevich J, Deas S, Polansky MM, Baedke DA,
Ingebritsen TS, Anderson RA, Graves DJ. Regulation of PTP-1 and insulin
receptor kinase by fractions from cinnamon: implications for cinnamon
regulation of insulin signaling. Horm Res. 1998 Sep;50(3):177-82. Lee JS, Jeon SM, Park EM, Huh TL, Kwon OS, Lee MK, Choi MS.
Cinnamate supplementation enhances hepatic lipid metabolism and antioxidant
defense systems in high cholesterol-fed rats. J Med Food. 2003
Fall;6(3):183-91. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes,
Inc.
5 mg.
What Is It?
Uses For Cinnulin PF™
What Is The Source?
Recommendations
Are There Any Potential Side Effects Or Precautions?
Are There Any Potential Drug Interactions?
References:
each vegetable capsule contains:
cinnamon (Cinnamomi cassia) extract (20:1) (bark)
125 mg.
vitamin C (as ascorbyl palmitate)
(hypo-allergenic plant fiber
added to complete capsule volume requirement)
2 capsules per day, in divided doses, with meals.
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