<A HREF="http://www.thegreenpharmacy.com" TITLE="The Green Pharmacy"><IMG SRC="https://store.nexternal.com/greenpharm/Logo-9thvector_Nexternal.jpg" ALT="The Green Pharmacy" NAME="The Green Pharmacy" BORDER=0></A><BR> <H1>Cat's Claw -- The Green Pharmacy Shopping Cart</H1> <B>$17.95</B> -- <I>Support for joint, cardiovascular, immune and gastrointestinal function</I> <P> <IMG SRC="https://store.nexternal.com/greenpharm/images/PE_Cat's_Claw.jpg" ALIGN=right ALT="Cat's Claw" NAME="Cat's Claw" BORDER=0 HSPACE=10> <style> <!-- h5 { font-family: Arial; font-size: 12pt; color: #008000; font-weight: bold; border-bottom: 1px dotted #008000; margin-top: 12; margin-bottom: 0; padding: 1px } numbered list small { list-style-type: decimal; font-family: Arial; font-size: 8pt; text-align: left; line-height: 11pt; margin-left: 5; margin-top: 6; margin-bottom: 6 } body { font-family: Arial; font-size: 11pt } .body1 { font-family: Arial; font-size: 11pt; line-height: 14pt; margin-top: 4; margin-bottom: 8 } .body2 { font-family: Arial; font-size: 11pt; line-height: 14pt; margin-top: 8; margin-bottom: 4 } .table1 { font-family: Arial; font-size: 12pt; color: #008000; font-weight: bold; padding-top: 1px; padding-bottom: 1px } --> </style> <font FACE="Arial-Bold"><b> <h5 ALIGN="LEFT">What Is It?</h5> </b></font><font FACE="Arial" SIZE="1"> <p ALIGN="LEFT" class="body1">Cat&#8217;s claw, Uncaria tomentosa, is an herbal extract. It has been used traditionally in Peru for over 2,000 years. Alkaloids, phenols, sterols and glycosides comprise some of the naturally occurring constituents of this herb.</p> </font><b><font FACE="Univers-Bold"> <h5 ALIGN="LEFT">Uses For Cat&#8217;s Claw</font></h5> </b><font FACE="Univers" SIZE="1"> <p ALIGN="LEFT" class="body1"><b>Joint Health:</b> In a 52-week, randomized double blind trial, cat's claw extract promoted joint comfort in volunteers. A 4-week study also suggests that cat's claw has the ability to promote joint comfort, in part by moderating prostaglandin metabolism. Other mechanisms of action that may account for these effects include modulation of both oxidative stress and cytokine production.* </p> <p ALIGN="LEFT" class="body1"><b>Cardiovascular Health:</b> Cardiovascular protective properties include support for healthy vascular and platelet function.* </p> <p ALIGN="LEFT" class="body1"><b>Immune Support:</b> Cat&#8217;s claw alkaloids have been specifically associated with enhancing immune system cell function, including phagocytosis and macrophage activity.* </p> <p ALIGN="LEFT" class="body1"><b>Gastrointestinal Health:</b> Studies involving cultured gastric epithelial cells suggest that cat's claw may provide important antioxidant protection for gut health.* </p> </font><font FACE="Univers-Bold"><b> <h5 ALIGN="LEFT">What Is The Source?</h5> </b></font><font FACE="Univers" SIZE="1"> <p ALIGN="LEFT" class="body1">This extract is sourced from the inner vine bark of Cat&#8217;s claw (Uncaria tomentosa). It is standardized to contain 3% oxindole alkaloids (2.73% POAs and 0.27% TOAs) and 15% polyphenols. Vitamin C (ascorbyl palmitate) is derived from corn dextrose fermentation.</p> </font><font FACE="Univers-Bold"><b> <h5 ALIGN="LEFT">Recommendations</h5> </b></font><font FACE="Univers" SIZE="1"> <p ALIGN="LEFT" class="body1">Pure Encapsulations recommends 1-6 capsules per day, in divided doses, with meals.</p> </font><font FACE="Univers-Bold"><b> <h5 ALIGN="LEFT">Are There Any Potential Side Effects Or Precautions?</h5> </b></font><font FACE="Univers" SIZE="1"> <p ALIGN="LEFT" class="body1">Mild gastrointestinal discomfort has been reported in some cases. Not to be taken by pregnant or lactating women.</p> </font><font FACE="Univers-Bold"><b> <h5 ALIGN="LEFT">Are There Any Potential Drug Interactions?</h5> </b></font><font FACE="Univers" SIZE="1"> <p ALIGN="LEFT" class="body1">Cat&#8217;s claw may be contraindicated for individuals who are taking blood thinning or antihypertensive medications due to a potential synergistic effect. </p> </font><font FACE="Univers-Bold"><b> <h5 ALIGN="LEFT">References:</h5> </b></font><font SIZE="1"> <ol> <li> <p ALIGN="LEFT">Mur E, Hartig F, Eibl G, Schirmer M. Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of uncaria tomentosa for the treatment of rheumatoid arthritis. J Rheumatol. 2002 Apr;29(4):678-81. </li> <li> <p ALIGN="LEFT">Piscoya J, Rodriguez Z, Bustamante SA, Okuhama NN, Miller MJ, Sandoval M. Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis. nflamm Res. 2001 Sep;50(9):442-8. </li> <li> <p ALIGN="LEFT">Riva L, Coradini D, Di Fronzo G, De Feo V, De Tommasi N, De Simone F, Pizza C. The antiproliferative effects of Uncaria tomentosa extracts and fractions on the growth of breast cancer cell line. Anticancer Res. 2001 Jul- Aug;21(4A):2457-61. </li> <li> <p ALIGN="LEFT">Sandoval-Chacon M, Thompson JH, Zhang XJ, Liu X, Mannick EE, Sadowska-Krowicka H, Charbonnet RM, Clark DA, Miller MJ. Antiinflammatory actions of cat's claw: the role of NF-kappaB. Aliment Pharmacol Ther. 1998 Dec;12(12):1279-89. </li> <li> <p ALIGN="LEFT">Miller MJ, Angeles FM, Reuter BK, Bobrowski P, Sandoval M. Dietary antioxidants protect gut epithelial cells from oxidantinduced apoptosis. BMC Complement Altern Med. 2001;1(1):11. </li> <li> <p ALIGN="LEFT">Sandoval M, Charbonnet RM, Okuhama NN, Roberts J, Krenova Z, Trentacosti AM, Miller MJ. Cat's claw inhibits TNFalpha production and scavenges free radicals: role in cytoprotection. Free Radic Biol Med. 2000 Jul 1;29(1):71-8. </li> <li> <p ALIGN="LEFT">Healthnotes Clinical Essentials. Copyright 2004. Healthnotes, Inc.</li> </ol> <font face="Arial" size="2" color="#2A4591"> <b>each vegetable capsule contains:</b><table width="405" cellpadding="0" cellpadding="0"> <tr> <td width="329" background="/images/dots2.gif" nowrap> <font color="#2a4591" face="Arial" size="2"> <span style="background-image: url('/images/white_pixel.gif')" class="LeftLink1"> cat's claw (Uncaria tomentosa) extract</span></font><font size="2"> </font></td> <td width="70" background="/images/dots2.gif" align="right" nowrap> <font color="#2a4591" face="Arial" size="2"> <span style="background-image: url('/images/white_pixel.gif')" class="LeftLink1"> 500 mg.</span></font><font size="2"> </font></td></tr> <tr><td colspan="2"> <font color="#2a4591" face="Arial" size="2">(standardized to contain 3% oxindole alkaloids and 15% polyphenols)</font><font size="2"> </font> </td></tr> <tr> <td width="329" background="/images/dots2.gif" nowrap> <font color="#2a4591" face="Arial" size="2"> <span style="background-image: url('/images/white_pixel.gif')" class="LeftLink1"> vitamin C (as ascorbyl palmitate)</span></font><font size="2"> </font> </td> <td width="70" background="/images/dots2.gif" nowrap> <p align="right"><font color="#2a4591" face="Arial" size="2"> <span style="background-image: url('/images/white_pixel.gif')" class="LeftLink1"> 10 mg.</span></font><font size="2"> </font> </td></tr> </table></font></font> <p><font color="#2a4591" face="Arial" size="2"><i>Not to be taken by pregnant or lactating women. </i></font> </p> <p><font color="#2a4591" face="Arial" size="2">1&#8211;6 capsules per day, in divided doses, with meals.</font></p></P> <P><B>Other products in the category <A HREF="http://www.nexternal.com/greenpharm/Category1" TITLE="General Store">General Store</A>:</B> <BR clear=left><BR><A HREF=http://www.nexternal.com/greenpharm/Product731 TITLE="1000-K Alternative Formula 90 cplts"><IMG SRC="https://store.nexternal.com/greenpharm/images/DL_1000_K_Alternative_Formula1.jpg" HEIGHT=120 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caps" NAME="Acetyl-L-Carnitine 250 mg 60 caps" BORDER=0 HSPACE=10></A> <A HREF=http://www.nexternal.com/greenpharm/Product983 TITLE="Acetyl-L-Carnitine 250 mg 60 caps">Acetyl-L-Carnitine 250 mg 60 caps</A> -- Positively affects brain chemistry, supporting memory, mood, and energy production* <BR clear=left><BR><A HREF=http://www.nexternal.com/greenpharm/Product21 TITLE="Acetyl-L-Carnitine 250 mg. 60 caps"><IMG SRC="https://store.nexternal.com/greenpharm/images/ACET5.jpg" WIDTH=80 ALIGN=left ALT="Acetyl-L-Carnitine 250 mg. 60 caps" NAME="Acetyl-L-Carnitine 250 mg. 60 caps" BORDER=0 HSPACE=10></A> <A HREF=http://www.nexternal.com/greenpharm/Product21 TITLE="Acetyl-L-Carnitine 250 mg. 60 caps">Acetyl-L-Carnitine 250 mg. 60 caps</A> -- A safe and natural nutritional support of healthy mental functioning </P> <BR clear=left><BR><P><A HREF="http://www.nexternal.com/greenpharm" TITLE="The Green Pharmacy Products">The Green Pharmacy Products</A></P> <BR clear=left><BR><BR><BR><BR> <BR><A 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