
De-Mer-Tox™ capsules, provided by Douglas
Laboratories®, contain several vitamins and other dietary constituents
supportive of metabolic processes that may protect against the toxic stress of
amalgam filling removal. “Silver” amalgam tooth fillings are known to
continuously release highly neurotoxic mercury vapor into the mouth where it is
then absorbed into the brain. This mercury release is greatly accentuated during
the extensive grinding required for the replacement of old amalgam fillings.
There is some evidence that adverse metabolic and behavioral effects may be
associated with this mercury exposure from dental amalgam fillings. Although
symptoms of chronic, low level mercury exposure may be relatively non-descript,
severe signs of toxicity may appear later in life. Research has shown that
chronic inhalation of low levels of mercury vapor can inhibit polymerization of
the brain protein tubulin which is essential for the formation and maintenance
of neuron microtubular structure. Mercury can also disassemble these neuronal
microtubules. Mercury, a sulfhydryl-reactive metal, can affect a wide variety of
metabolic processes. It is not only a prooxidant, but also inhibits antioxidant
enzymes and depletes intracellular glutathione. L-glutathione (reduced), a
naturally occurring tripeptide of L-cysteine, L-glutamate, and L-glycine, is the
essential cosubstrate for two major antioxidant enzymes in the body, glutathione
peroxidase and glutathione reductase. N-acetyl-L-cysteine is a precursor for the
sulfur amino acid cysteine, used in the synthesis of glutathione. Dietary sulfur
may play an important role in mercury detoxification as studies have shown an
inverse relationship between non-protein sulfhydryl levels and mercury organ
content. Thus, an increased body level of non-protein sulfhydryls may avoid
mercury accumulation and its deleterious effects. Consequently, it may be most
beneficial to provide the improved nutritional detoxification support of De-Mer-Tox™
capsules during the removal of amalgam fillings. De-Mer-Tox™ capsules may be a useful dietary
supplement for individuals who wish improve their nutritional detoxification
systems during the stress of amalgam filling removal. Adults take 2 capsules daily or as directed by
physician. No adverse effects have been reported. Store in a cool, dry place, away from direct
light. Keep out of reach of children. Quig, D. Cysteine metabolism and metal toxicity. Altern Med
Rev 1998;3:262-70. Echeverria, D, Aposhian, HV, Woods, JS, Heyer, NJ, Aposhian,
MM, Bittner, AC, Jr., Mahurin, RK, Cianciola, M. Neurobehavioral effects
from exposure to dental amalgam Hg(o): new distinctions between recent
exposure and Hg body burden. Faseb J 1998;12:971-80. Yoneda, S, Suzuki, KT. Detoxification of mercury by selenium
by binding of equimolar Hg-Se complex to a specific plasma protein. Toxicol
Appl Pharmacol 1997;143:274-80. Pendergrass, JC, Haley, BE, Vimy, MJ, Winfield, SA,
Lorscheider, FL. Mercury vapor inhalation inhibits binding of GTP to tubulin
in rat brain: similarity to a molecular lesion in Alzheimer diseased brain.
Neurotoxicology 1997;18:315-24. Sandborgh-Englund, G, Nygren, AT, Ekstrand, J, Elinder, CG.
No evidence of renal toxicity from amalgam fillings [see comments]. Am J
Physiol 1996;271:R941-5. Marchi, A, Piana, G. [Amalgam and the toxicological risks of
mercury. A review of the argument]. Minerva Stomatol 1995;44:311-8. Ziff, MF. Documented clinical side-effects to dental
amalgam. Adv Dent Res 1992;6:131-4. Willershausen-Zonnchen, B, Zimmermann, M, Defregger, A,
Schramel, P, Hamm, G. [Mercury concentration in the mouth mucosa of patients
with amalgam fillings]. Dtsch Med Wochenschr 1992;117:1743-7. Girardi, G, Elias, MM. Effectiveness of N-acetylcysteine in
protecting against mercuric chloride-induced nephrotoxicity. Toxicology
1991;67:155-64. Taskinen, H, Kinnunen, E, Riihimaki, V. A possible case of
mercury-related toxicity resulting from the grinding of old amalgam
restorations. Scand J Work Environ Health 1989;15:302-4. 250 mg 100 mg *These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure, or
prevent any disease.
Description
Functions
Indications
Suggested Use
Side Effects/Warnings
Storage
References:
Two Capsules
Contain:
L-Glutathione (reduced)
50 mg
N-Acetyl-L-Cysteine
500 mg
Dietary Sulfur
500 mg
Seleno-Methionine
100 mcg
Biotin
200 mcg
Thiamin
25 mg
Riboflavin
10 mg
Garlic
(Pure-Gar)
Parsley
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