
Hyaluronic acid, or HA, is a naturally occurring
polymer found in every tissue of the body. It is particularly concentrated in
the skin (almost 50% of all HA in the body is found in the skin) and synovial
fluid. It is composed of alternating units of n-acetyl-d-glucosamine and d-glucuronate.
This polymer's functions include attracting and retaining water in the
extracellular matrix of tissues, in layers of skin, and in synovial fluid.* Easily Absorbed: In nature, HA is a large
molecular weight compound, ranging in size from 500,000-6,000,000 daltons.
This is too large to be absorbed in the small intestines. Pure
Encapsulations HA has undergone a sophisticated, patent-pending enzymatic
process that alters the molecular weight, though not
chemicalcomposition. The final result is an easily absorbed HA polymer
with a molecular weight of 5,000 daltons. Preliminary Research: Subjective evaluations
conducted by scientists at a Japanese university involved 96 individuals.
The reports suggest an enhancement of skin and joint health using low
molecular weight HA. A number of anecdotal and preliminary results also
indicate a positive effect on skin and joint health.* Skin Health: For skin cells, the ability of
HA to attract and retain water is essential for proper cell-to-cell
communication, hydration, nutrient delivery, and waste and toxin elimination. HA
also appears to support the skin by promoting healthy turnover and renewal of
keratinocytes, moderating the appearance of fine lines and age spots.* Joint Health: For joints, HA is especially
supportive of healthy lubrication and shock absorption. Furthermore, in vitro
studies indicate that HA modulates prostaglandin production, providing
additional support for joint function.* The source of Pure Encapsulations Hyaluronic acid
is rooster comb. Hypo-allergenic plant fiber is derived from pine cellulose. Pure Encapsulations recommends taking 6 capsules
per day (providing 37.8 mg HA), in divided doses, with or between meals. At this time, there are no known side effects or
precautions. If pregnant or lactating, consult your physician before taking this
product. At this time, there are no known adverse reactions
when taken in conjunction with medications. Sakai S, Yasuda R, Sayo T, Ishikawa O, Inoue S. Hyaluronan
exists in the normal stratum corneum. J Invest Dermatol 2000
Jun;114(6):1184-7. Meyer LJ, Stern R. Age-dependent changes of hyaluronan in
human skin. J Invest Dermatol 1994 Mar;102(3):385-9. Ghersetich I, Lotti T, Campanile G, Grappone C, Dini G.
Hyaluronic acid in cutaneous intrinsic aging. Int J Dermatol 1994
Feb;33(2):119-22. Manna F, Dentini M, Desideri P, De Pita O, Mortilla E, Maras
B. Comparative chemical evaluation of two commercially available derivatives
of hyaluronic acid (hylaform from rooster combs and restylane from
streptococcus) used for soft tissue augmentation. J Eur Acad Dermatol
Venereol 1999 Nov;13(3):183-92. Altman RD. Status of hyaluronan supplementation therapy in
osteoarthritis. Curr Rheumatol Rep 2003 Feb;5(1):7-14. Omori, Seiji. Panel Study on Injuv (low molecular weight
hyaluronic acid). Otsuma Universtiy, Japan, 2000. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes,
Inc.
What Is It?
Features Include
Uses For Hyaluronic Acid
What Is The Source?
Recommendations
Are There Any Potential Side Effects Or Precautions?
Are There Any Potential Drug Interactions?
References:
each vegetable capsule contains:
hyaluronic acid powder
70 mg.
(providing
a minimum of 9% hyaluronic acid)
(hypo-allergenic
plant fiber added to complete capsule volume requirement)
other
ingredients: maltodextrin
6 capsules per day, in divided doses, with or between meals.
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