
Dual Source Chromium, produced by Douglas
Laboratories®, supplies 300 mcg of dietary chromium in two highly bioavailable
forms, chromium polynicotinate and chromium picolinate Chromium is an essential trace mineral that
potentiates insulin action and thus influences carbohydrate, protein, and fat
metabolism. The biologically active form of chromium, sometimes called glucose
tolerance factor (GTF), occurs naturally in brewers yeast. GTF has been proposed
to be a complex of chromium, nicotinic acid (vitamin B-3), and possibly the
amino acids glycine, cysteine and glutamic acid. Although many attempts have
been made to isolate or synthesize GTF, none have been entirely successful.
Adequate chromium nutrition is essential for the formation of GTF and subsequent
control of blood glucose levels. Studies have shown that chromium may be useful
for the maintenance of healthy blood sugar. Chromium appears to act by
increasing insulin binding, insulin receptor numbers and rate of insulin
receptor phosphorylation. Chromium absorption is typically less than 2%
efficient and variable depending on its chemical form. Both chromium picolinate
and chromium polynicotinate are highly bioavailable forms that can be retained
in tissues anywhere from 2 to 8 times better than chromium chloride. The typical
chromium intake in diet can vary considerably depending on eating habits. Meats
and unrefined whole grain cereal products especially bran, are good sources of
chromium. However, most self-selected diets contain less than 50 mcg per day,
which is below the minimum of the Estimated Safe and Adequate Daily Dietary
Intake, established by the National Research Council, Food and Nutrition Board. Dual Source Chromium may be useful as a dietary
supplement for individuals who wish to supplement their intake of chromium or
have a demonstrated need for supplemental chromium in its active form due to
dietary deficiency or impaired metabolism. Adults take 1 capsule daily with meals or as
directed by physician. No adverse effects have been reported. Store in a cool, dry place, away from direct
light. Keep out of reach of children. Anderson RA. Chromium, glucose intolerance and diabetes. J
Am Coll Nutr 1998;17:548-55. Anderson RA, Bryden NA, Polansky MM. Lack of toxicity of
chromium chloride and chromium picolinate in rats. J Am Coll Nutr
1997;16:273-9. Anderson RA, Cheng N, Bryden NA, et al. Elevated intakes of
supplemental chromium improve glucose and insulin variables in individuals
with type 2 diabetes. Diabetes 1997;46:1786-91. Bahadori B, Wallner S, Schneider H, et al. [Effect of
chromium yeast and chromium picolinate on body composition of obese,
nondiabetic patients during and after a formula diet]. Acta Med Austriaca
1997;24:185-7. *These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure, or
prevent any disease.
Description
Functions
Indications
Suggested Use
Side Effects/Warnings
Storage
References:
Each Capsule
Contains:
Chromium (picolinate)
150 mcg
Chromium GTF (polynicotinate)
150 mcg
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