
Cal-6 + Mg.™, provided by Douglas Laboratories, is
a special chelate complex of 6 sources of calcium with magnesium and other
ingredients to assist the body in maintaining healthy bone structure. Calcium is
a primary mineral for building the strong structure of bones and teeth. The adult human body contains approximately 1,200
g of calcium, about 99% of which is present in the skeleton, and 20-30 g of
magnesium with about 60% located in bone. Bone is constantly turning over, a
continuous process of formation and resorption. In children and adolescents, the
rate of formation of bone mineral predominates over the rate of resorption. In
later life, resorption predominates over formation. Therefore, in normal aging,
there is a gradual loss of bone. Intestinal calcium absorption ranges from 15 to
75% of ingested calcium. Vitamin D is a key regulatory hormone for calcium and
bone metabolism. Adequate vitamin D status is essential for ensuring normal
calcium absorption and maintenance of healthy calcium plasma levels. Magnesium
absorption is independent of vitamin D status and ranges from 30 to 60% of
ingested magnesium. Osteoporosis, a condition of reduced bone mineral
density that can increase risk of fractures, affects a large proportion of the
elderly in developed countries. Caucasian and Asian women typically have low
peak bone densities, and therefore, are at the greatest risk of developing
osteoporosis. It is generally accepted that obtaining enough dietary calcium
throughout life can significantly decrease the risk of developing osteoporosis.
Among other factors, such as regular exercise, gender and race, calcium
supplementation during childhood and adolescence appears to be a prerequisite
for maintaining adequate bone density later in life. But even elderly
osteoporotic patients can benefit significantly from supplementation with
dietary calcium. Cal-6 + Mg.™ provides a highly beneficial source
of dietary calcium together with other nutrients that assist in the maintenance
of healthy bone structure and function. For example, boron affects the
composition, structure, and strength of bone. It appears to be necessary for
calcium and magnesium absorption, their adequate renal reabsorption, and their
incorporation into the bone matrix. Boron is absorbed at about 90% efficiency
and is rapidly distributed among the tissues. Cal-6 + Mg.™ may be a useful dietary supplement
for those who wish to increase their intake of calcium and other nutritional
factors for maintaining the function and structure of their bones. Adults take 1 tablet before each meal or as
directed by physician. No adverse effects have been reported Store in a cool, dry place, away from direct
light. Keep out of reach of children. Barger-Lux MJ, Heaney RP. The role of calcium intake in
preventing bone fragility, hypertension, and certain cancers. J Nutr
1994;124:1406S-1411S. Bendich A, Leader S, Muhuri P. Supplemental calcium for the
prevention of hip fracture: potential health-economic benefits. Clin Ther
1999;21:1058-72. Bronner F. Calcium and osteoporosis. Am J Clin Nutr
1994;60:831-6. Bronner F, Pansu D. Nutritional aspects of calcium
absorption. J Nutr 1999;129:9-12. Castelo-Branco C. Management of osteoporosis. An overview.
Drugs Aging 1998;12:25-32. Celotti F, Bignamini A. Dietary calcium and mineral/vitamin
supplementation: a controversial problem. J Int Med Res 1999;27:1-14. Chapin RE, Ku WW, Kenney MA, McCoy H, Gladen B, Wine RN,
Wilson R, Elwell MR. The effects of dietary boron on bone strength in rats.
Fundam Appl Toxicol 1997;35:205-15. Epstein O, Kato Y, Dick R, Sherlock S. Vitamin D,
hydroxyapatite, and calcium gluconate in treatment of cortical bone thinning
in postmenopausal women with primary biliary cirrhosis. Am J Clin Nutr
1982;36:426-30. Fleming KH, Heimbach JT. Consumption of calcium in the U.S.:
food sources and intake levels. J Nutr 1994;124:1426S-1430S. Meacham SL, Taper LJ, Volpe SL. Effect of boron
supplementation on blood and urinary calcium, magnesium, and phosphorus, and
urinary boron in athletic and sedentary women. Am J Clin Nutr 1995;61:341-5.
Meunier PJ, Delmas PD, Eastell R, McClung MR, Papapoulos S,
Rizzoli R, Seeman E, Wasnich RD. Diagnosis and management of osteoporosis in
postmenopausal women: clinical guidelines. International Committee for
Osteoporosis Clinical Guidelines. Clin Ther 1999;21:1025-44. Nielsen FH. The justification for providing dietary guidance
for the nutritional intake of boron. Biol Trace Elem Res 1998;66:319-30.
O'Brien KO. Combined calcium and vitamin D supplementation
reduces bone loss and fracture incidence in older men and women. Nutr Rev
1998;56:148-50. Patrick L. Comparative absorption of calcium sources and
calcium citrate malate for the prevention of osteoporosis. Altern Med Rev
1999;4:74-85. Pines A, Raafat H, Lynn AH, Whittington J. Clinical trial of
microcrystalline hydroxyapatite compound ('Ossopan') in the prevention of
osteoporosis due to corticosteroid therapy. Curr Med Res Opin 1984;8:734-42.
Reid IR. The roles of calcium and vitamin D in the
prevention of osteoporosis. Endocrinol Metab Clin North Am 1998;27:389-98.
Sojka JE, Weaver CM. Magnesium supplementation and
osteoporosis. Nutr Rev 1995;53:71-4. Stellon A, Davies A, Webb A, Williams R. Microcrystalline
hydroxyapatite compound in prevention of bone loss in corticosteroid-treated
patients with chronic active hepatitis. Postgrad Med J 1985;61:791-6. *These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure, or
prevent any disease.
Description
Functions
Indications
Suggested Use
Side Effects/Warnings
Storage
References:
Three Tablets
Contain:
Calcium (elemental)
750 mg
Glutamic Acid HCl
75 mg
Lysine HCl
36 mg
Boron (Aspartate/Citrate)
3 mg
Vitamin D-3
400 I.U.
Magnesium (elemental)
375 mg
Vitamin C
50 mg
In a base of Silica
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