
Rosmarinic Acid Extract
Life Extension, 60 caps
Allergies are characterized by the excess proliferation of immune responder cells in the bloodstream and nasal fluids.1 This enormous influx of responder cells to the airways and nasal passages produces the congestion, fluid outpouring and swelling that allergy sufferers find so debilitating. While traditional antihistamines lessen some of these symptoms by preventing the release of histamine from mast cells or blocking histamine receptor sites, they do nothing to prevent the excess activation or proliferation of immune responder cells.2
Rosmarinic acid extract is a new alternative to painful allergy shots and pills that provide only partial relief from allergic symptoms. Rosmarinic acid, a plant polyphenol derived from rosemary leaf, provides effective, temporary relief of allergy symptoms. Unlike antihistamines, rosmarinic acid both prevents the activation of immune responder cells and kills excess allergy-activated immune cells.
The Rosmarinic Acid Extract formula also contains perilla leaf extract. In a landmark study, scientists demonstrated that perilla leaf enriched with rosmarinic acid provided significant relief from seasonal allergies by inhibiting polymorphonuclear leukocyte infiltration into the nostrils.3 In addition, the Rosmarinic Acid Extract formula includes luteolin, another plant flavonoid that has been shown to maintain normal respiratory function and healthy fluid balance.4
With ingredients that both act as antihistamines and restrict the activation and proliferation of allergy-related responder cells, Rosmarinic Acid Extract stops allergy miseries at their source.
1 Costa JJ, Welker PF, Galli SJ. The cells of the allergic response: mast cells, basophils, and eosinophls, JAMA. 1997 Dec 10;278(22):1815-22.
2 Wong BR, Grossbard EB, Payan DB, Masuda ES, Targeting Syk as a treatment for allergic and autoimmune disorders. Expert Opin Investi Drugs. 2004 Jul;13(7)743-62.
3 Takano H, Osakabe N, Sanbongi C et al. Extract of Perilla frutescens enriched for rosmarinic acid inhibits seasonal allergic rhinoconjunctivitis in humans. Exp Biol Med. 2004 Mar;229(3):247-54.
4 Ueda H, Yamazaki C. Luteolin as an anti-inflammatory and antiallergic constituent of Perilla frutescens. Biol Pharm Bull. 2002 Sep;25(9):1197-202.
Supplement Facts
Serving Size 1 capsule
Servings Per Container 60
Amount Per Serving
Rosmarinic acid(from Rosmarinus officinalis leaf extract) 100 mg
Luteolin [from perilla leaf extract (Perilla frutescens)] 4 mg
Perilla leaf 4:1 extract (Perilla frutescens) 50 mg
Other ingredients: rice flour, gelatin, maltodextrin, magnesium stearate
Dosage and Use
Take one to two capsules in the morning after a meal or as directed by a healthcare practitioner.
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