
Maintaining strong, healthy bones is a cornerstone
to successful aging. Unfortunately, even health-conscious adults often fail to
consume enough calcium, vitamin D, and other nutrients shown to protect against
age-related loss of bone mineral density. Take five capsules at dinner or before bedtime, or
as recommended by a healthcare practitioner. Fruitex B® is a registered trademark of VDF
Futureceuticals, Inc. *These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure, or
prevent any disease.
What is it?
Throughout life, cells known as osteoblasts construct bone matrix and fill it
with calcium. At the same time, cells called osteoclasts work just as busily to
tear down and reabsorb the bone. This fine balance is regulated by many factors,
including systemic hormones and cytokines. Bone mass reaches its peak by the
middle of the third decade of life and plateaus for about ten years, during
which time bone turnover is constant, with bone formation approximately equaling
bone resorption.
As our bodies age, this fine balance is lost. As the relative hormone levels
shift in midlife—more drastically in women than in men—the osteoclasts gain the
upper hand and bone mass begins dwindling away. Some bone is already being lost
by the time women reach menopause, but the rate of loss can increase as much as
tenfold during the first six years after menopause.
From midlife onward, bone health is threatened by overactive osteoclasts. To add
to the problem, the osteoblasts may become less active from age 60 onward.
Whereas trabecular (spongy-looking) bone in the vertebrae and elsewhere was
formerly at risk from excess osteoclast activity, now the cortical (dense) bone
of the hip, shin, pelvis, and other sites becomes more prone to fracturing
because osteoblasts do not make enough of it.
Calcium is the most popular mineral supplement on the market, yet certain forms
of calcium tablets are often poorly absorbed by the digestive systems of older
people because of insufficient stomach acid. The Life Extension Foundation
Buyers Club supplies calcium and almost all other mineral supplements only in
the form of finely divided mineral powders within capsules that easily
disintegrate in the stomach for optimal absorption. Studies have also shown that
certain mineral compounds are absorbed better than others.
Calcium is the most abundant mineral in the body where it is primarily found in
bones and teeth. In bone formation, calcium forms crystals that provide strength
to maturing bone. Peak bone mass is usually achieved when people are in their
20’s.
Calcium is needed for more than just healthy bones. It is also important for
muscle contraction, blood vessel contraction and expansion, the secretion of
hormones and enzymes, and sending messages through the nervous system. A
meta-analysis of 56 clinical trials demonstrated a significant impact on heart
health resulting from increasing calcium intake by 1000 to 2000 mg/day. In
addition, recent evidence suggests that increased intake of calcium may help in
weight control as well.
Magnesium is one of the body’s most important minerals. It is required as a
co-factor in hundreds of enzymatic processes within cells. It helps maintain
normal muscle and nerve function, keeps heart rhythm steady, supports a healthy
immune system, and keeps bones strong.* Magnesium also helps to maintain blood
sugar and blood pressure levels already within normal range, and is known to be
involved in energy metabolism and protein synthesis.*
Magnesium is a major factor in relaxing the smooth muscles within the blood
vessels, thereby reducing peripheral vascular resistance and promoting a healthy
cardiovascular system.* Magnesium also affects circulating levels of
norepinephrine and the synthesis of serotonin and nitric oxide.
In bone mineral health, magnesium (or lack of) influences the bone mineral
matrix and its ability to metabolize minerals needed for repair and rebuilding.
The scientific literature documents the need for a wide range of minerals that
are vital to maintaining strong, healthy bones.*
Calcium and other minerals are best not taken with fiber, because fiber can
interfere with their absorption. There is evidence that calcium from supplements
and dairy foods may inhibit iron absorption, although it has been very difficult
to distinguish between the effects of calcium on iron absorption versus other
inhibitory factors such as phytate.
Therefore, if you are iron deficient, it may be best to avoid taking calcium
with meals. Calcium supplements are best administered at dinner and/or bedtime.
They should always be taken with a full glass of water, juice, or other liquid
to enhance solubility. If calcium-containing formulas are taken only once daily
they may be best taken in the evening.
Engaging in regular weight-bearing exercise, eating a variety of healthy foods,
and avoiding tobacco and alcohol, can help maintain healthy bones. Foods that
promote bone health include calcium sources—such as dark green leafy vegetables,
broccoli, legumes, canned salmon, and sardines—and dairy products like milk and
cheese.
A problem overlooked by most doctors is that loss of bone density is associated
with deficiencies of not just calcium, but a host of other nutrients including
magnesium and vitamin D3. New research on vitamin D has led an increasing number
of experts to advise men and women over the age of 50 to protect against bone
loss by consuming 800-1000 IU (and higher) of vitamin D each day.
In order for calcium to prevent bone loss, adequate amounts of vitamin D3, zinc,
manganese and other nutrients should be available so that calcium, magnesium,
and phosphorus can be incorporated into the bone matrix. Another issue that many
people are not aware of is that many forms of calcium do not absorb particularly
well.
In order to overcome the impediments that preclude aging women and men from
achieving optimal calcium status, a mineral formula has been designed that
provides 1200 elemental milligrams from three different forms of calcium per
daily dose, along with critically important nutrients needed to promote healthy
bones. Bone Restore delivers a potent dose of magnesium, along with nutrients
that enable calcium and magnesium to be incorporated in the bone matrix, like
boron and silicon to further boost the body’s ability to maintain healthy bone
density.*
Boron has been identified as one of the most important nutrients to help
maintain bone health. As such, Life Extension has incorporated a powerful form
of boron, called FruiteX B® OsteoBoron™, which is more bioavailable than boron
citrate, the nutrient used in most commercial bone building supplements.
FruiteX B® OsteoBoron™ is made from a naturally occurring boron complex found in
fruits and vegetables. Its unique boron-carbohydrate structure that easily binds
to fructose may be one of the reasons for its health benefits. Boron in general
is a crucial mineral in bone/joint health. Numerous studies have shown boron to
contribute to the structural integrity of bone.Suggested Use
Total intake of calcium greater than 2000 mg per day provides no added benefit
to bone health. Supplement Facts
Supplement Facts
Serving Size 5 capsules
Servings Per Container 30
Amount Per Serving
Calcium (as dicalcium
malate, calcium bis-glycinate, calcium fructoborate)
1200 mg
Vitamin D3 (as
cholecalciferol)
1000 IU
Magnesium (as magnesium
oxide)
340 mg
Boron (calcium fructoborate
as patented Fruitex B® OsteoBoron™)
3 mg
Zinc (as zinc amino acid
chelate)
2 mg
Manganese (as manganese
amino acid chelate)
1 mg
Silicon (from horsetail
herb, Equisetum arvense)
5 mg
Other
ingredients: gelatin, magnesium stearate.
Contains corn. This product contains NO milk,
egg, fish, peanuts, crustacean shellfish, soybeans, tree nuts,
wheat, yeast, gluten, or rice. Contains NO artificial
sweeteners, flavors, colors, or preservatives.
OsteoBoron™ is a trademark of VDF Futureceuticals, Inc.
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