
l-Alpha-glycerophophatidylcholine (GPC-choline,
alpha-GPC) is a water-soluble phospholipid and neurotransmitter precursor
naturally occurring in the body. Unlike most membrane phospholipids, alpha-GPC
is water-soluble because it lacks the hydrophobic tail groups. Memory And Cognitive Health: Alpha-GPC passes
through the blood brain barrier providing a source of choline for
acetylcholine and phosphatidylcholine biosynthesis. By supporting cell
membrane fluidity and integrity, phosphatidylcholine enhances healthy
neurotransmitter function and signal transduction. Alpha-GPC may support
healthy phospholipid turnover in the brain, helping to counteract
age-related cellular breakdown of membrane phospholipids. Acetylcholine is a
key neurotransmitter in the brain supporting memory and learning. Optimal
phospholipid and acetylcholine levels support cognitive, mental and
cerebrovascular health.* Growth Hormone Support: Alpha-GPC has the
ability to potentiate growth hormone releasing hormone (GHRH), thereby
supporting healthy growth hormone (GH) levels. The mechanism of support
appears to involve increased cholinergic tone.* Alpha-GPC is derived from highly purified soy
lecithin. Vitamin C (ascorbyl palmitate) is derived from corn dextrose
fermentation. Hypo-allergenic plant fiber is derived from pine cellulose. There
is no detectable GMO material in this product. Pure Encapsulations recommends 1 capsule (400 mg
of Alpha-GPC, standardized to contain 50% L-alphaglycerophosphatidylcholine),
three times per day, with or between meals. If pregnant or lactating, consult your physician
before taking this product. May cause some gastrointestinal irritation, headache
or insomnia in a small percentage of people. At this time, there are no known adverse reactions
when taken in conjunction with medications. P M Kidd. Phospholipids: Versatile Nutraceutical Ingredients
For Functional Foods. Functional Foods and Nutraceuticals. December 2002.
Barbagallo Sangiorgi G, Barbagallo M, Giordano M, Meli M,
Panzarasa R. alpha-Glycerophosphocholine in the mental recovery of cerebral
ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci
1994 Jun 30;717:253-69. Parnetti L, Abate G, Bartorelli L, Cucinotta D, Cuzzupoli M,
Maggioni M, Villardita C, Senin U. Multicentre study of l-alpha-glyceryl-phosphorylcholine
vs ST200 among patients with probable senile dementia of Alzheimer's
type. Drugs Aging 1993 Mar-Apr;3(2):159-64. Ceda GP, Ceresini G, Denti L, Marzani G, Piovani E, Banchini
A, Tarditi E, Valenti G. alpha-Glycerylphosphorylcholine administration
increases the GH responses to GHRH of young and elderly subjects. Horm
Metab Res 1992 Mar;24(3):119-21 Healthnotes Clinical Essentials. Copyright 2004. Healthnotes,
Inc.
200 mg.
20 mg.
What Is It?
Uses For Alpha-GPC
What Is The Source?
Recommendations
Are There Any Potential Side Effects Or Precautions?
Are There Any Potential Drug Interactions?
References:
each vegetable capsule contains:
stabilized alpha-GPC (L-alpha- glycerophosphatidylcholine)
400 mg.
providing 50% L-alpha- glycerophosphatidylcholine
vitamin C (as ascorbyl palmitate)
(hypo-allergenic plant fiber
added to complete capsule volume requirement)
other ingredients: calcium
phosphate, silicon dioxide
3 capsules per day, in divided doses, with or between meals.
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