
Cal//Mag 2001 tablets from Douglas Laboratories®
provide 750 mg of elemental calcium from a calcium citrate/ascorbate complex,
together with significant amounts of magnesium from an aspartate/ascorbate
complex, as well as vitamin D-3. Other nutrients are also included to assist the
body in maintaining healthy bone structure. The adult human body contains approximately 1,200
g of calcium, about 99% of which is present in the skeleton, and 20-30 g of
magnesium with about 60% located in bone. Bone is constantly turning over, a
continuous process of formation and resorption. In children and adolescents, the
rate of formation of bone mineral predominates over the rate of resorption. In
later life, resorption predominates over formation. Therefore, in normal aging,
there is a gradual loss of bone. Intestinal calcium absorption ranges from 15 to
75% of ingested calcium. Vitamin D is a key regulatory hormone for calcium and
bone metabolism. Adequate vitamin D status is essential for ensuring normal
calcium absorption and maintenance of healthy calcium plasma levels. Magnesium
absorption is independent of vitamin D status and ranges from 30 to 60% of
ingested magnesium. Osteoporosis, a condition of reduced bone mineral
density that can increase risk of fractures, affects a large proportion of the
elderly in developed countries. Caucasian and Asian women typically have low
peak bone densities, and therefore, are at the greatest risk of developing
osteoporosis. It is generally accepted that obtaining enough dietary calcium
throughout life can significantly decrease the risk of developing osteoporosis.
Among other factors, such as regular exercise, gender and race, calcium
supplementation during childhood and adolescence appears to be a prerequisite
for maintaining adequate bone density later in life. But even elderly
osteoporotic patients can benefit significantly from supplementation with
dietary calcium. Cal/Mag 2001 provides a highly beneficial source
of dietary calcium together with other nutrients that assist in the maintenance
of healthy bone structure and function. For example, boron affects the
composition, structure, and strength of bone. It appears to be necessary for
calcium and magnesium absorption, their adequate renal reabsorption, and their
incorporation into the bone matrix. Boron is absorbed at about 90% efficiency
and is rapidly distributed among the tissues. Cal//Mag 2001 may be a useful dietary supplement
for those who wish to increase their intake of calcium and other nutritional
factors for maintaining good bone health. Adults take 3 tablets daily or as directed by
physician. No adverse effects have been reported. Store in a cool, dry place, away from direct
light. Keep out of reach of children. Bendich A, Leader S, Muhuri P. Supplemental calcium for the
prevention of hip fracture: potential health-economic benefits. Clin Ther
1999;21:1058-72. Castelo-Branco C. Management of osteoporosis. An overview.
Drugs Aging 1998;12:25-32. Chapin RE, Ku WW, Kenney MA, et al. The effects of dietary
boron on bone strength in rats. Fundam Appl Toxicol 1997;35:205-15. Dimai HP, Porta S, Wirnsberger G, et al. Daily oral
magnesium supplementation suppresses bone turnover in young adult males. J
Clin Endocrinol Metab 1998;83:2742-8. Laketic-Ljubojevic I, Suva LJ, Maathuis FJ, et al.
Functional characterization of N-methyl-D-aspartic acid-gated channels in
bone cells. Bone 1999;25:631-7. Morton DJ, Barrett-Connor EL, Schneider DL. Vitamin C
supplement use and bone mineral density in postmenopausal women.[In Process
Citation]. J Bone Miner Res 2001;16:135-40. New SA, Robins SP, Campbell MK, et al. Dietary influences on
bone mass and bone metabolism: further evidence of a positive link between
fruit and vegetable consumption and bone health? Am J Clin Nutr
2000;71:142-51. O'Brien KO. Combined calcium and vitamin D supplementation
reduces bone loss and fracture incidence in older men and women. Nutr Rev
1998;56:148-50. Reid IR. The roles of calcium and vitamin D in the
prevention of osteoporosis. Endocrinol Metab Clin North Am 1998;27:389-98.
Rude RK, Kirchen ME, Gruber HE, et al. Magnesium deficiency
induces bone loss in the rat. Miner Electrolyte Metab 1998;24:314-20. *These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat, cure, or
prevent any disease.
Description
Functions
Indications
Suggested Use
Side Effects/Warnings
Storage
References:
Three Tablets
Contain:
Calcium
750 mg
(Citrate/Ascorbate
Complex)
Magnesium
375 mg
(Aspartate/Ascorbate
Complex)
Vitamin D-3
75 I.U.
Vitamin C
150 mg
(Calcium/Magnesium
Ascorbate)
Boron (Asparate/Citrate)
3 mg
Glutamic Acid HCl
150 mg
All in a specially
acidified base
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