
l-Carnitine is an amino acid found abundantly in
skeletal and heart muscle. It functions primarily to support fat utilization by
acting as a carrier of fatty acids into the mitochondria, where they are
oxidized and converted to energy. l-Carnitine also facilitates the removal of
short and medium chain fatty acids from the mitochondria that accumulate during
normal metabolic processes. In studies, l-carnitine has demonstrated the ability
to promote oxygenation of heart muscle and maintain healthy enzyme activity,
support cardiovascular energy, enhance exercise recovery, and maintain healthy
lipid metabolism.* Cardiovascular Support: A randomized
double-blind placebo-controlled trial involving 101 volunteers indicated that l-carnitine
maintained healthy lipid peroxide and lactate dehydrogenase cardiac enzyme
activity. l-Carnitine may also support ventricular function and superoxide
dismutase enzyme activity. Long-term l-carnitine supplementation has
demonstrated positive support for cardiovascular health after a 3-year follow-up
in adult subjects. In a recent six-month, randomized, double-blind
placebo-controlled trial, l-carnitine supplementation supported healthy lipid
metabolism in volunteers.* Support For Exercise Recovery: A recent
placebo-controlled clinical study conducted at Ball State University in Indiana
found that l-carnitine- -tartrate supplementation significantly supported
physical recovery from high intensity exercise. This allows for less tissue
damage, decreased production of free radicals and less muscle soreness following
exercise. In a prospective double-blind placebo-controlled trial, carnitine
supplementation supported training for elite athletes.* l-Carnitine-l-tartrate contains 68% pure l-carnitine
and 32% natural l-tartaric acid. l-Carnitine-l-tartrate is synthetically
produced. Vitamin C (ascorbyl palmitate) is derived from corn dextrose
fermentation and palm oil. Hypo-allergenic plant fiber is derived from pine
cellulose. Pure Encapsulations recommends 2-4 capsules per
day, in divided doses, between meals. At this time, there are no known side effects or
precautions. If pregnant or lactating, consult your physician before taking this
product. At this time, there are no known adverse reactions
when taken in conjunction with medications. Singh RB, Niaz MA, Agarwal P, Beegum R, Rastogi SS, Sachan
DS. A randomized, double-blind, placebo-controlled trial of l-carnitine in
suspected acute myocardial infarction. Postgrad Med J 1996
Jan;72(843):45-50. Kobayashi A, Masumura Y, Yamazaki N. L-carnitine treatment
for congestive heart failure--experimental and clinical study. Jpn Circ
J.1992 Jan;56(1):86-94. Loster H et al. Prolonged oral L-carnitine substitution
increases bicycle ergometer performance in patients with severe,
ischemically induced cardiac insufficiency. Cardiovasc Drugs Ther.1999
Nov;13(6) 537-46. Derosa G et al. The effect of L-carnitine on plasma
lipoprotein(a) levels in hypercholesterolemic patients with type 2 diabetes
mellitus. Clin Ther.2003May;25(5):1429-39. Gurlek A et al.The effects of L-carnitine treatment on left
ventricular function and erythrocyte superoxide dismutase activity in
patients with ischemic cardiomyopathy. Eur J Heart Fail.2000 Jun;2(2):189-
3. Rizos I. Three-year survival of patients with heart failure
caused by dilated cardiomyopathy and L-carnitine administration. Am Heart
J.2000 Feb;139(2 Pt 3):S120-3. Vecchiet L et al. Influence of L-carnitine administration on
maximal physical exercise. Eur J Appl Physiol Occup
Physiol.1990;61(5-6):486-90. Dragan GI, Vasiliu A, Georgescu E, Dumas I. Studies
concerning chronic and acute effects of L-carnitine on some biological
parameters in elite athletes. Physiologie. 1987 Jan-Mar;24(1):23-8 Healthnotes Clinical Essentials. Copyright 2004. Healthnotes,
Inc. 12 mg.
What Is It?
Uses For l-Carnitine
What Is The Source?
Recommendations
Are There Any Potential Side Effects Or Precautions?
Are There Any Potential Drug Interactions?
References:
each vegetable capsule contains:
l-carnitine (free-form)
340 mg.
(from 500 mg. of l-carnitine-l-
tartrate)
vitamin C (as ascorbyl palmitate)
(hypo-allergenic plant fiber added to
complete capsule volume requirement)
2–4 capsules per day, in divided doses, between meals.
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